Entity Details

Primary name CNO6L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96LI5
EntryNameCNO6L_HUMAN
FullNameCCR4-NOT transcription complex subunit 6-like
TaxID9606
Evidenceevidence at protein level
Length555
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesCNOT6L

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006397 mRNA processing
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008284 positive regulation of cell population proliferation
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0030014 CCR4-NOT complex
GO:0031047 gene silencing by RNA
GO:0046872 metal ion binding
GO:0061157 mRNA destabilization

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR034967 CCR4-NOT transcription complex subunit 6-likeDomainDomain
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
CNO6L_HUMANCNOT8_HUMANBioGRID, IntAct, UniProt17452450 29395067 32296183 details
CNO6L_HUMANCNOT7_HUMANBioGRID, DIP, IntAct, UniProt17452450 21984185 26186194 27173435 28514442 29395067 32296183 unassigned1312 details
CNO6L_HUMANTNR6A_HUMANBioGRID, UniProt21981923 21984185 29395067 details
CNO6L_HUMANLZTR1_HUMANBioGRID, IntAct20211142 details
CNO6L_HUMANZSCA1_HUMANBioGRID, IntAct20211142 details
CNO6L_HUMANTOB1_HUMANBioGRID, IntAct, UniProt18377426 28514442 details
CNO6L_HUMANTB182_HUMANBioGRID, IntAct, UniProt17452450 27173435 29395067 unassigned1312 details
CNO6L_HUMANCNOT3_HUMANBioGRID, UniProt17452450 29395067 details
CNO6L_HUMANCNO10_HUMANBioGRID, IntAct, UniProt17452450 27173435 29395067 unassigned1312 details
CNO6L_HUMANCNOT2_HUMANBioGRID, IntAct, UniProt17452450 26496610 27173435 29395067 unassigned1312 details
CNO6L_HUMANCNOT9_HUMANBioGRID, UniProt17452450 29395067 details
CNO6L_HUMANCAF1B_HUMANBioGRID, UniProt17452450 details
CNO6L_HUMANCNOT1_HUMANBioGRID, DIP, IntAct, UniProt17452450 21984185 22977175 26496610 29395067 details
CNO6L_HUMANTNR6C_HUMANBioGRID, DIP, UniProt21981923 21984185 29395067 details
CNO6L_HUMANAGO2_HUMANBioGRID, UniProt21981923 29395067 details
CNO6L_HUMANTNR6B_HUMANBioGRID, UniProt21981923 29395067 details
CNO6L_HUMANNFKB1_HUMANBioGRID, IntAct27173435 unassigned1312 details
CNO6L_HUMANCNO11_HUMANBioGRID, IntAct27173435 28514442 29395067 unassigned1312 details
CNO6L_HUMANCNOT6_HUMANIntActunassigned1312 details
CNO6L_HUMANGPBL1_HUMANBioGRID, IntAct28514442 29395067 details
CNO6L_HUMANCAF1A_HUMANBioGRID17452450 details
CNO6L_HUMANRC3H1_HUMANBioGRID26170170 29395067 details
CNO6L_HUMANTTP_HUMANBioGRID21078877 29395067 details
CNO6L_HUMANHELZ_HUMANBioGRID29395067 details
CNO6L_HUMANOBI1_HUMANBioGRID29395067 details
CNO6L_HUMANYTHD2_HUMANBioGRID29395067 details
CNO6L_HUMANZ3H7A_HUMANBioGRID29395067 details
CNO6L_HUMANMEX3B_HUMANBioGRID29395067 details
CNO6L_HUMANUNK_HUMANBioGRID29395067 details
CNO6L_HUMANYTHD3_HUMANBioGRID29395067 details
CNO6L_HUMANTBKB1_HUMANBioGRID29395067 details
CNO6L_HUMANCPEB4_HUMANBioGRID29395067 details
CNO6L_HUMANDDX6_HUMANBioGRID29395067 details
CNO6L_HUMANPRC2A_HUMANBioGRID29395067 details
CNO6L_HUMANTOP3B_HUMANBioGRID29395067 details
CNO6L_HUMANUBP2L_HUMANBioGRID29395067 details