Entity Details

Primary name K1C12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99456
EntryNameK1C12_HUMAN
FullNameKeratin, type I cytoskeletal 12
TaxID9606
Evidenceevidence at protein level
Length494
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesKRT12

GO terms

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GOName
GO:0002009 morphogenesis of an epithelium
GO:0005198 structural molecule activity
GO:0005829 cytosol
GO:0005882 intermediate filament
GO:0007601 visual perception
GO:0031424 keratinization
GO:0061303 cornea development in camera-type eye
GO:0070062 extracellular exosome
GO:0070268 cornification

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002957 Keratin, type IFamilyFamily
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00400 GriseofulvinDrugbanksmall molecule
DB11157 AnthralinDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
K1C12_HUMANUCHL5_HUMANBioGRID21800051 details
K1C12_HUMANTRAF6_HUMANBioGRID27507811 details