Entity Details

Primary name PI51A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99755
EntryNamePI51A_HUMAN
FullNamePhosphatidylinositol 4-phosphate 5-kinase type-1 alpha
TaxID9606
Evidenceevidence at protein level
Length562
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesPIP5K1A

GO terms

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GOName
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006650 glycerophospholipid metabolic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0006909 phagocytosis
GO:0007165 signal transduction
GO:0008654 phospholipid biosynthetic process
GO:0010761 fibroblast migration
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016477 cell migration
GO:0016607 nuclear speck
GO:0019900 kinase binding
GO:0030027 lamellipodium
GO:0030216 keratinocyte differentiation
GO:0031532 actin cytoskeleton reorganization
GO:0032587 ruffle membrane
GO:0048041 focal adhesion assembly
GO:0060326 cell chemotaxis
GO:0072659 protein localization to plasma membrane
GO:0090630 activation of GTPase activity
GO:0097178 ruffle assembly

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, coreDomainDomain
IPR023610 Phosphatidylinositol-4-phosphate 5-kinaseFamilyFamily
IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminalFamilyHomologous superfamily

Diseases

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