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Entity Details
Primary name
CCM2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9BSQ5
EntryName
CCM2_HUMAN
FullName
Cerebral cavernous malformations 2 protein
TaxID
9606
Evidence
evidence at protein level
Length
444
SequenceStatus
complete
DateCreated
2005-10-11
DateModified
2021-06-02
Ontological Relatives
Genes
CCM2
GO terms
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GO
Name
GO:0001570
vasculogenesis
GO:0001701
in utero embryonic development
GO:0001885
endothelial cell development
GO:0005737
cytoplasm
GO:0005739
mitochondrion
GO:0007229
integrin-mediated signaling pathway
GO:0032991
protein-containing complex
GO:0035264
multicellular organism growth
GO:0045216
cell-cell junction organization
GO:0048839
inner ear development
GO:0048845
venous blood vessel morphogenesis
GO:0051403
stress-activated MAPK cascade
GO:0060039
pericardium development
GO:0060837
blood vessel endothelial cell differentiation
GO:0061154
endothelial tube morphogenesis
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR006020
PTB/PI domain
Domain
Domain
IPR026159
Cerebral cavernous malformations 2
Family
Family
IPR032375
Cerebral cavernous malformations 2, harmonin-homology domain
Domain
Domain
Diseases
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Drugs
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Interactions
16 interactions
Interactor
Partner
Sources
Publications
Link
CCM2_HUMAN
PDC10_HUMAN
DIP, IntAct, MINT
17657516
23266514
27027284
details
CCM2_HUMAN
KRIT1_HUMAN
BioGRID, DIP, IntAct
17657516
23007647
25525273
25814554
25910212
27027284
28514442
details
CCM2_HUMAN
SRPK2_HUMAN
BioGRID, IntAct
23602568
details
CCM2_HUMAN
CCM2_HUMAN
MINT
23266514
details
CCM2_HUMAN
DOK4_HUMAN
BioGRID, IntAct
25814554
details
CCM2_HUMAN
VTM2L_HUMAN
BioGRID, IntAct
25814554
details
CCM2_HUMAN
TWST2_HUMAN
BioGRID, IntAct
25814554
details
CCM2_HUMAN
POTE1_HUMAN
bhf-ucl, BioGRID
21044950
details
CCM2_HUMAN
HXC8_HUMAN
BioGRID, IntAct
32296183
details
CCM2_HUMAN
TLRN1_HUMAN
BioGRID, IntAct
32296183
details
CCM2_HUMAN
RIN1_HUMAN
BioGRID, IntAct
32296183
details
CCM2_HUMAN
M3K3_HUMAN
DIP
25982527
27027284
details
CCM2_HUMAN
SMUF1_HUMAN
BioGRID
19318350
31623230
details
CCM2_HUMAN
STK25_HUMAN
IntAct
17657516
details
CCM2_HUMAN
SMUF2_HUMAN
BioGRID
19318350
details
CCM2_HUMAN
RHOA_HUMAN
BioGRID
31623230
details
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