Entity Details

Primary name CSN4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BT78
EntryNameCSN4_HUMAN
FullNameCOP9 signalosome complex subunit 4
TaxID9606
Evidenceevidence at protein level
Length406
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesCOPS4

GO terms

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GOName
GO:0000338 protein deneddylation
GO:0000715 nucleotide-excision repair, DNA damage recognition
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0008021 synaptic vesicle
GO:0008180 COP9 signalosome
GO:0016607 nuclear speck
GO:0030054 cell junction
GO:0043687 post-translational protein modification

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Nucleus

Domains

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DomainNameCategoryType
IPR000717 Proteasome component (PCI) domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037754 COP9 signalosome complex subunit 4FamilyFamily
IPR040134 26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4FamilyFamily
IPR041406 COP9 signalosome complex subunit 4, helix turn helix domainDomainDomain

Diseases

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Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
CSN4_HUMANBRME1_HUMANBioGRID, HPRD, IntAct16189514 details
CSN4_HUMANRCBT2_HUMANBioGRID, HPRD, IntAct16189514 details
CSN4_HUMANCC85B_HUMANBioGRID, HPRD, IntAct16189514 details
CSN4_HUMANUSBP1_HUMANBioGRID, HPRD, IntAct16189514 25416956 26871637 details
CSN4_HUMANMBIP1_HUMANBioGRID, HPRD, IntAct16189514 details
CSN4_HUMANCSN5_HUMANBioGRID, DIP, HPRD, IntAct11285227 11337588 14647295 16624822 18850735 19295130 19615732 20399188 21145461 22863883 23086934 24725084 26186194 26344197 27173435 28514442 31950832 32034103 9707402 unassigned1312 details
CSN4_HUMANCSN6_HUMANBioGRID, DIP, HPRD, IntAct11285227 11337588 14647295 19141280 19295130 19615732 21145461 22863883 22939629 23086934 25043011 26186194 26344197 27173435 28514442 31444342 32034103 32296183 9707402 unassigned1312 details
CSN4_HUMANFOS_HUMANBioGRID, IntAct20195357 details
CSN4_HUMANTOR1A_HUMANBioGRID, MINT21102408 details
CSN4_HUMANCSN7A_HUMANBioGRID, HPRD, IntAct11285227 11337588 14647295 17403899 19141280 19295130 22863883 22939629 23086934 26344197 26496610 27833851 9707402 details
CSN4_HUMANK1C19_HUMANBioGRID, IntAct26871637 details
CSN4_HUMANCSN8_HUMANBioGRID, DIP, HPRD, IntAct11285227 11337588 14647295 19295130 22863883 22939629 23086934 24981860 25043011 26344197 27173435 28514442 9707402 unassigned1312 details
CSN4_HUMANPCDBC_HUMANBioGRID, IntAct32296183 details
CSN4_HUMANPEX14_HUMANBioGRID, IntAct32296183 details
CSN4_HUMANCSN2_HUMANBioGRID, DIP, HPRD, IntAct11285227 11337588 14647295 16045761 19295130 22863883 22939629 24981860 25043011 26186194 26344197 27173435 28514442 31444342 32034103 9707402 unassigned1312 details
CSN4_HUMANCSN7B_HUMANBioGRID, IntAct19295130 22863883 22939629 26344197 27173435 27833851 28514442 32034103 unassigned1312 details
CSN4_HUMANCSN3_HUMANBioGRID, DIP, HPRD, IntAct11285227 11337588 14647295 16036220 19295130 20399188 22863883 22939629 24981860 25043011 26186194 26344197 28514442 32034103 9707402 details
CSN4_HUMANCSN1_HUMANBioGRID, DIP11114242 19295130 20399188 22414063 22863883 22939629 25043011 26344197 27029275 32034103 details
CSN4_HUMANNUP58_HUMANIntAct32814053 details
CSN4_HUMANDDB1_HUMANBioGRID16949367 16964240 19295130 22767593 details
CSN4_HUMANIKKB_HUMANBioGRID19656241 details
CSN4_HUMANRBX1_HUMANBioGRID19295130 30349055 31444342 details
CSN4_HUMAN1433T_HUMANBioGRID15161933 details
CSN4_HUMANHEMGN_HUMANBioGRID24740910 details
CSN4_HUMANUBQL1_HUMANBioGRID26871637 details
CSN4_HUMANIL1RA_HUMANBioGRID15749898 details
CSN4_HUMANCSN4_HUMANBioGRID, HPRD12615944 32034103 details
CSN4_HUMANARF6_HUMANIntAct17353931 details
CSN4_HUMAN1433Z_HUMANMINT15161933 details
CSN4_HUMANSYT1_HUMANMINT21102408 details
CSN4_HUMANCUL4B_HUMANBioGRID, IntAct, MINT19295130 21145461 23238014 24292684 24981860 26496610 28225217 31973889 details
CSN4_HUMANCUL1_HUMANBioGRID, IntAct16036220 19295130 21145461 29103612 details
CSN4_HUMANCUL4A_HUMANBioGRID, IntAct16964240 17079684 18606781 19295130 21145461 31973889 details
CSN4_HUMANCUL2_HUMANBioGRID, IntAct19295130 21145461 details
CSN4_HUMANNEDD8_HUMANBioGRID, IntAct16503656 21145461 details
CSN4_HUMANCUL3_HUMANBioGRID, IntAct19295130 21145461 28514442 details
CSN4_HUMANCUL5_HUMANBioGRID, HPRD, IntAct11337588 21145461 31253590 details
CSN4_HUMANP53_HUMANBioGRID, HPRD, MINT11285227 22653443 24725084 details
CSN4_HUMANDDB2_HUMANBioGRID, IntAct12732143 16260596 19295130 26186194 26496610 28514442 details
CSN4_HUMANBTBD1_HUMANBioGRID, IntAct19295130 28514442 details
CSN4_HUMANCRBN_HUMANBioGRID, DIP19295130 24292625 27029275 details
CSN4_HUMANERCC8_HUMANBioGRID12732143 19295130 29531219 details
CSN4_HUMANDCAF1_HUMANBioGRID18606781 19295130 details
CSN4_HUMANPTN14_HUMANBioGRID22948661 27432908 details
CSN4_HUMANSNAPN_HUMANBioGRID21102408 details
CSN4_HUMANSTON2_HUMANBioGRID21102408 details
CSN4_HUMANERPG3_HUMANBioGRID22032989 26030138 details
CSN4_HUMANERCC6_HUMANBioGRID22032989 26030138 details
CSN4_HUMANDTL_HUMANBioGRID16861906 19295130 21628527 details
CSN4_HUMANGCYA1_HUMANBioGRID24725084 details
CSN4_HUMANCSK21_HUMANBioGRID24725084 details
CSN4_HUMANIBTK_HUMANBioGRID25882842 details
CSN4_HUMANSIR7_HUMANBioGRID28886238 details
CSN4_HUMANIRF5_HUMANBioGRID29339435 details
CSN4_HUMANSHLD2_HUMANBioGRID30154076 details