Entity Details

Primary name SGPP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BX95
EntryNameSGPP1_HUMAN
FullNameSphingosine-1-phosphate phosphatase 1
TaxID9606
Evidenceevidence at protein level
Length441
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GenesSGPP1

GO terms

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GOName
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006668 sphinganine-1-phosphate metabolic process
GO:0006670 sphingosine metabolic process
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030148 sphingolipid biosynthetic process
GO:0035621 ER to Golgi ceramide transport
GO:0042392 sphingosine-1-phosphate phosphatase activity
GO:0045616 regulation of keratinocyte differentiation
GO:0045682 regulation of epidermis development
GO:0046839 phospholipid dephosphorylation
GO:0070780 dihydrosphingosine-1-phosphate phosphatase activity
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097193 intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidaseDomainDomain
IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SGPP1_HUMANUBC_HUMANBioGRID28190767 details