Entity Details

Primary name LAMA5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15230
EntryNameLAMA5_HUMAN
FullNameLaminin subunit alpha-5
TaxID9606
Evidenceevidence at protein level
Length3695
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesLAMA5

GO terms

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GOName
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001738 morphogenesis of a polarized epithelium
GO:0001755 neural crest cell migration
GO:0001942 hair follicle development
GO:0005178 integrin binding
GO:0005201 extracellular matrix structural constituent
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005610 laminin-5 complex
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0007229 integrin-mediated signaling pathway
GO:0007411 axon guidance
GO:0007517 muscle organ development
GO:0009887 animal organ morphogenesis
GO:0009888 tissue development
GO:0016331 morphogenesis of embryonic epithelium
GO:0016477 cell migration
GO:0019221 cytokine-mediated signaling pathway
GO:0030155 regulation of cell adhesion
GO:0030198 extracellular matrix organization
GO:0030324 lung development
GO:0030334 regulation of cell migration
GO:0031594 neuromuscular junction
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042127 regulation of cell population proliferation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043083 synaptic cleft
GO:0043259 laminin-10 complex
GO:0043260 laminin-11 complex
GO:0045995 regulation of embryonic development
GO:0060271 cilium assembly
GO:0060445 branching involved in salivary gland morphogenesis
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072659 protein localization to plasma membrane
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000034 Laminin IVDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001368 TNFR/NGFR cysteine-rich regionDomainDomain
IPR001791 Laminin G domainDomainDomain
IPR002049 Laminin EGF domainDomainDomain
IPR008211 Laminin, N-terminalDomainDomain
IPR009254 Laminin alpha, domain IDomainDomain
IPR010307 Laminin domain IIDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB06245 LanoteplaseDrugbankbiotech