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Entity Details
Primary name
EIF2A_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9BY44
EntryName
EIF2A_HUMAN
FullName
Eukaryotic translation initiation factor 2A
TaxID
9606
Evidence
evidence at protein level
Length
585
SequenceStatus
complete
DateCreated
2007-05-01
DateModified
2021-06-02
Ontological Relatives
Genes
EIF2A
GO terms
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GO
Name
GO:0000049
tRNA binding
GO:0003729
mRNA binding
GO:0003743
translation initiation factor activity
GO:0005615
extracellular space
GO:0005737
cytoplasm
GO:0005850
eukaryotic translation initiation factor 2 complex
GO:0006417
regulation of translation
GO:0006468
protein phosphorylation
GO:0009967
positive regulation of signal transduction
GO:0022627
cytosolic small ribosomal subunit
GO:0032933
SREBP signaling pathway
GO:0042255
ribosome assembly
GO:0043022
ribosome binding
GO:0045296
cadherin binding
GO:0072562
blood microparticle
GO:1990928
response to amino acid starvation
Subcellular Location
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Domains
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Domain
Name
Category
Type
IPR011387
Translation initiation factor 2A
Family
Family
IPR013979
Translation initiation factor, beta propellor-like domain
Domain
Domain
IPR015943
WD40/YVTN repeat-like-containing domain superfamily
Family
Homologous superfamily
IPR036322
WD40-repeat-containing domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
10 interactions
Interactor
Partner
Sources
Publications
Link
EIF2A_HUMAN
MLH1_HUMAN
BioGRID, IntAct
20706999
details
EIF2A_HUMAN
A4_HUMAN
BioGRID
21832049
details
EIF2A_HUMAN
E2AK2_HUMAN
BioGRID
19229320
29070839
details
EIF2A_HUMAN
BZW2_HUMAN
BioGRID
21745818
details
EIF2A_HUMAN
ATF4_HUMAN
BioGRID
15475356
details
EIF2A_HUMAN
DCC_HUMAN
BioGRID
20434207
details
EIF2A_HUMAN
NXF1_HUMAN
BioGRID
18337511
details
EIF2A_HUMAN
ILF3_HUMAN
BioGRID
18337511
details
EIF2A_HUMAN
RS6_HUMAN
BioGRID
21745818
details
EIF2A_HUMAN
CAPR1_HUMAN
BioGRID
29395067
details
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