Entity Details

Primary name NSD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BZ95
EntryNameNSD3_HUMAN
FullNameHistone-lysine N-methyltransferase NSD3
TaxID9606
Evidenceevidence at protein level
Length1437
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesNSD3

GO terms

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GOName
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0016571 histone methylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0046975 histone methyltransferase activity (H3-K36 specific)
GO:0140537 transcription regulator activator activity
GO:2001255 positive regulation of histone H3-K36 trimethylation

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000313 PWWP domainDomainDomain
IPR001214 SET domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR006560 AWS domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR041306 NSD, Cys-His rich domainDomainDomain

Diseases

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Interactions

59 interactions

InteractorPartnerSourcesPublicationsLink
NSD3_HUMANCBX3_HUMANBioGRID, IntAct20936779 34079125 details
NSD3_HUMANCBX5_HUMANBioGRID, IntAct, MINT21516116 25416956 32814053 details
NSD3_HUMANDAXX_HUMANBioGRID, MINT23455924 details
NSD3_HUMANDOCK7_HUMANBioGRID, MINT23455924 details
NSD3_HUMANETV3_HUMANBioGRID, MINT23455924 details
NSD3_HUMANGLYR1_HUMANBioGRID, MINT23455924 details
NSD3_HUMANH3C_HUMANBioGRID, MINT23455924 details
NSD3_HUMANH11_HUMANBioGRID, MINT23455924 details
NSD3_HUMANHXC4_HUMANBioGRID, MINT23455924 details
NSD3_HUMANMNDA_HUMANBioGRID, MINT23455924 details
NSD3_HUMANSEPT6_HUMANBioGRID, MINT23455924 details
NSD3_HUMANSLU7_HUMANBioGRID, MINT23455924 details
NSD3_HUMANSPAG8_HUMANBioGRID, MINT23455924 details
NSD3_HUMANSTAC3_HUMANBioGRID, MINT23455924 details
NSD3_HUMANUBC9_HUMANBioGRID, MINT23455924 details
NSD3_HUMANZNF57_HUMANMINT23455924 details
NSD3_HUMANATM_HUMANBioGRID, MINT25640309 details
NSD3_HUMANAKT1_HUMANBioGRID, MINT25640309 details
NSD3_HUMANBCAR3_HUMANBioGRID, MINT25640309 details
NSD3_HUMANCASP8_HUMANBioGRID, MINT25640309 details
NSD3_HUMANCDN2A_HUMANBioGRID, MINT25640309 details
NSD3_HUMANCHK2_HUMANBioGRID, MINT25640309 details
NSD3_HUMANESR1_HUMANBioGRID, IntAct, MINT25640309 31527615 details
NSD3_HUMANFGFR4_HUMANBioGRID, MINT25640309 details
NSD3_HUMANPAX2_HUMANBioGRID, MINT25640309 details
NSD3_HUMANPPM1D_HUMANBioGRID, MINT25640309 details
NSD3_HUMANRAD51_HUMANBioGRID, MINT25640309 details
NSD3_HUMANRBCC1_HUMANBioGRID, MINT25640309 details
NSD3_HUMANTGFB1_HUMANBioGRID, MINT25640309 details
NSD3_HUMANTRI63_HUMANBioGRID, IntAct31391242 details
NSD3_HUMANTRI55_HUMANBioGRID, IntAct31391242 details
NSD3_HUMANFGFR3_HUMANIntAct32814053 details
NSD3_HUMANRASH_HUMANIntAct32814053 details
NSD3_HUMANLMNA_HUMANBioGRID, IntAct32814053 34079125 details
NSD3_HUMANTGFR2_HUMANIntAct32814053 details
NSD3_HUMANSPRE1_HUMANIntAct32814053 details
NSD3_HUMANBRD4_HUMANBioGRID21555454 24875858 26626481 29176719 31753913 32416067 details
NSD3_HUMANZN557_HUMANBioGRID23455924 details
NSD3_HUMANH31T_HUMANBioGRID23269674 details
NSD3_HUMANAF17_HUMANBioGRID25416956 details
NSD3_HUMANARF_HUMANBioGRID25640309 details
NSD3_HUMANH31_HUMANBioGRID25494638 26912663 34079125 details
NSD3_HUMANH4_HUMANBioGRID25494638 30804502 details
NSD3_HUMANSOX4_HUMANBioGRID28205554 details
NSD3_HUMANMYC_HUMANBioGRID28205554 details
NSD3_HUMANNSD3_HUMANBioGRID28205554 details
NSD3_HUMANCBLC_HUMANBioGRID28205554 details
NSD3_HUMANGLIS2_HUMANBioGRID28205554 details
NSD3_HUMANNFIC_HUMANBioGRID28205554 details
NSD3_HUMANSOX3_HUMANBioGRID28205554 details
NSD3_HUMANTFE2_HUMANBioGRID28205554 details
NSD3_HUMANTEAD2_HUMANBioGRID28205554 details
NSD3_HUMANTERT_HUMANBioGRID28205554 details
NSD3_HUMANKDM1B_HUMANBioGRID, IntAct20670891 26496610 details
NSD3_HUMANCLUS_HUMANIntAct31413325 details
NSD3_HUMANCCNT1_HUMANBioGRID20670891 details
NSD3_HUMANBPTF_HUMANBioGRID26626481 details
NSD3_HUMANBD1L1_HUMANBioGRID26626481 details
NSD3_HUMANCHD8_HUMANBioGRID26626481 details