Entity Details

Primary name TRIM6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9C030
EntryNameTRIM6_HUMAN
FullNameTripartite motif-containing protein 6
TaxID9606
Evidenceevidence at protein level
Length488
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesTRIM6

GO terms

Show/Hide Table
GOName
GO:0000209 protein polyubiquitination
GO:0002230 positive regulation of defense response to virus by host
GO:0002720 positive regulation of cytokine production involved in immune response
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0010468 regulation of gene expression
GO:0010508 positive regulation of autophagy
GO:0010629 negative regulation of gene expression
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0010994 free ubiquitin chain polymerization
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0019901 protein kinase binding
GO:0030674 protein-macromolecule adaptor activity
GO:0032496 response to lipopolysaccharide
GO:0032880 regulation of protein localization
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035458 cellular response to interferon-beta
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045071 negative regulation of viral genome replication
GO:0045087 innate immune response
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046596 regulation of viral entry into host cell
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:0061630 ubiquitin protein ligase activity
GO:0098586 cellular response to virus
GO:1990782 protein tyrosine kinase binding
GO:2000679 positive regulation of transcription regulatory region DNA binding
GO:2000737 negative regulation of stem cell differentiation

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000315 B-box-type zinc fingerDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001870 B30.2/SPRY domainDomainDomain
IPR003877 SPRY domainDomainDomain
IPR003879 Butyrophylin-like, SPRY domainDomainDomain
IPR006574 SPRY-associatedDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR027370 RING-type zinc-finger, LisH dimerisation motifDomainDomain
IPR035828 TRIM6, PRY/SPRY domainDomainDomain
IPR043136 B30.2/SPRY domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table