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Entity Details
Primary name
UBA5_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9GZZ9
EntryName
UBA5_HUMAN
FullName
Ubiquitin-like modifier-activating enzyme 5
TaxID
9606
Evidence
evidence at protein level
Length
404
SequenceStatus
complete
DateCreated
2005-09-27
DateModified
2021-06-02
Ontological Relatives
Genes
UBA5
GO terms
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GO
Name
GO:0005524
ATP binding
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005789
endoplasmic reticulum membrane
GO:0005794
Golgi apparatus
GO:0005829
cytosol
GO:0008270
zinc ion binding
GO:0030218
erythrocyte differentiation
GO:0030219
megakaryocyte differentiation
GO:0032446
protein modification by small protein conjugation
GO:0033146
regulation of intracellular estrogen receptor signaling pathway
GO:0034976
response to endoplasmic reticulum stress
GO:0042803
protein homodimerization activity
GO:0043231
intracellular membrane-bounded organelle
GO:0050905
neuromuscular process
GO:0061709
reticulophagy
GO:0071566
UFM1 activating enzyme activity
GO:0071569
protein ufmylation
GO:1990592
protein K69-linked ufmylation
Subcellular Location
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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Golgi apparatus
Nucleus
Domains
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Domain
Name
Category
Type
IPR000594
THIF-type NAD/FAD binding fold
Domain
Domain
IPR029752
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
Site
Conserved site
IPR035985
Ubiquitin-activating enzyme
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
UBA5_HUMAN
ACPH_HUMAN
BioGRID, HPRD, IntAct
16189514
details
UBA5_HUMAN
GBRL2_HUMAN
BioGRID, HPRD, IntAct, MINT
16189514
20562859
21900206
25416956
28514442
32296183
details
UBA5_HUMAN
GBRAP_HUMAN
IntAct
20562859
details
UBA5_HUMAN
GBRL1_HUMAN
IntAct
20562859
details
UBA5_HUMAN
MLP3B_HUMAN
IntAct
20562859
details
UBA5_HUMAN
MLP3C_HUMAN
IntAct
20562859
details
UBA5_HUMAN
UFM1_HUMAN
BioGRID, IntAct
15071506
20562859
21304510
24966333
26496610
26872069
28514442
details
UBA5_HUMAN
UFC1_HUMAN
BioGRID, IntAct
20562859
24966333
28514442
details
UBA5_HUMAN
UB2L3_HUMAN
BioGRID
29643511
details
UBA5_HUMAN
UB2D2_HUMAN
BioGRID
29643511
details
UBA5_HUMAN
OGT1_HUMAN
BioGRID
32994395
details
UBA5_HUMAN
UBA5_HUMAN
BioGRID, IntAct
20368332
20562859
details
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