Entity Details

Primary name PKHA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HB21
EntryNamePKHA1_HUMAN
FullNamePleckstrin homology domain-containing family A member 1
TaxID9606
Evidenceevidence at protein level
Length404
SequenceStatuscomplete
DateCreated2004-03-29
DateModified2021-06-02

Ontological Relatives

GenesPLEKHA1

GO terms

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GOName
GO:0001553 luteinization
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006661 phosphatidylinositol biosynthetic process
GO:0007283 spermatogenesis
GO:0008209 androgen metabolic process
GO:0008210 estrogen metabolic process
GO:0008289 lipid binding
GO:0009791 post-embryonic development
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0016020 membrane
GO:0030165 PDZ domain binding
GO:0031529 ruffle organization
GO:0032587 ruffle membrane
GO:0033327 Leydig cell differentiation
GO:0035264 multicellular organism growth
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0045184 establishment of protein localization
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0050853 B cell receptor signaling pathway
GO:0051898 negative regulation of protein kinase B signaling
GO:0060021 roof of mouth development
GO:0060325 face morphogenesis
GO:0070062 extracellular exosome
GO:0070301 cellular response to hydrogen peroxide

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04272 Citric acidDrugbanksmall molecule