Entity Details

Primary name PLXA4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HCM2
EntryNamePLXA4_HUMAN
FullNamePlexin-A4
TaxID9606
Evidenceevidence at protein level
Length1894
SequenceStatuscomplete
DateCreated2006-06-13
DateModified2021-06-02

Ontological Relatives

GenesPLXNA4

GO terms

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GOName
GO:0002116 semaphorin receptor complex
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007162 negative regulation of cell adhesion
GO:0008360 regulation of cell shape
GO:0017154 semaphorin receptor activity
GO:0021612 facial nerve structural organization
GO:0021615 glossopharyngeal nerve morphogenesis
GO:0021637 trigeminal nerve structural organization
GO:0021644 vagus nerve morphogenesis
GO:0021784 postganglionic parasympathetic fiber development
GO:0021793 chemorepulsion of branchiomotor axon
GO:0021960 anterior commissure morphogenesis
GO:0030334 regulation of cell migration
GO:0043087 regulation of GTPase activity
GO:0048485 sympathetic nervous system development
GO:0048841 regulation of axon extension involved in axon guidance
GO:0050772 positive regulation of axonogenesis
GO:0050923 regulation of negative chemotaxis
GO:0071526 semaphorin-plexin signaling pathway
GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR002909 IPT domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR013548 Plexin, cytoplasmic RasGAP domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR031148 Plexin familyFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily
IPR041019 Plexin, TIG domain 1DomainDomain
IPR041362 Plexin, TIG domain 2DomainDomain

Diseases

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Interactions

3 interactions