Entity Details

Primary name CASS4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NQ75
EntryNameCASS4_HUMAN
FullNameCas scaffolding protein family member 4
TaxID9606
Evidenceevidence at protein level
Length786
SequenceStatuscomplete
DateCreated2002-10-10
DateModified2021-06-02

Ontological Relatives

GenesCASS4

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016477 cell migration
GO:0030335 positive regulation of cell migration
GO:0051897 positive regulation of protein kinase B signaling
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0090527 actin filament reorganization
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1990782 protein tyrosine kinase binding

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR014928 Serine rich protein interaction domainDomainDomain
IPR021901 CAS family, C-terminalDomainDomain
IPR035512 Cas scaffolding protein family member 4FamilyFamily
IPR035744 Cas scaffolding protein family member 4, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR037362 CAS familyFamilyFamily
IPR038319 CAS, serine rich four helix bundle domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
CASS4_HUMANZYX_HUMANBioGRID, IntAct31413325 32296183 details
CASS4_HUMANHSF2B_HUMANBioGRID, IntAct32296183 details
CASS4_HUMANGOGA2_HUMANIntAct32296183 details
CASS4_HUMANANS1B_HUMANBioGRID, IntAct31413325 32296183 details
CASS4_HUMANFHL3_HUMANBioGRID, IntAct32296183 details
CASS4_HUMANBORG1_HUMANBioGRID, IntAct31413325 32296183 details
CASS4_HUMANMICA1_HUMANBioGRID, IntAct28514442 31413325 details
CASS4_HUMANMD2L2_HUMANIntAct31413325 details
CASS4_HUMANSRBS1_HUMANIntAct31413325 details
CASS4_HUMANSPIN1_HUMANIntAct31413325 details
CASS4_HUMANCCD78_HUMANIntAct31413325 details
CASS4_HUMANDCTN1_HUMANIntAct31413325 details
CASS4_HUMANFAK2_HUMANIntAct31413325 details
CASS4_HUMANERCC1_HUMANIntAct31413325 details
CASS4_HUMANTRI32_HUMANIntAct31413325 details
CASS4_HUMANFLNA_HUMANIntAct31413325 details
CASS4_HUMANANS1A_HUMANIntAct31413325 details
CASS4_HUMANFYN_HUMANIntAct31413325 details
CASS4_HUMANT11L2_HUMANIntAct31413325 details
CASS4_HUMANBIP_HUMANIntAct31413325 details
CASS4_HUMANABLM1_HUMANIntAct31413325 details
CASS4_HUMANARRB1_HUMANIntAct31413325 details
CASS4_HUMANCRNL1_HUMANIntAct31413325 details
CASS4_HUMANDDX56_HUMANIntAct31413325 details
CASS4_HUMANF214A_HUMANIntAct31413325 details
CASS4_HUMANFAK1_HUMANIntAct31413325 details
CASS4_HUMANPTN12_HUMANIntAct31413325 details
CASS4_HUMANRU17_HUMANIntAct31413325 details
CASS4_HUMANTERF1_HUMANIntAct31413325 details
CASS4_HUMANREPS1_HUMANIntAct31413325 details
CASS4_HUMANMTMR2_HUMANIntAct31413325 details
CASS4_HUMANMTMR1_HUMANIntAct31413325 details
CASS4_HUMANRIMB1_HUMANIntAct31413325 details
CASS4_HUMANELMO1_HUMANIntAct31413325 details