Entity Details

Primary name DDX21_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR30
EntryNameDDX21_HUMAN
FullNameNucleolar RNA helicase 2
TaxID9606
Evidenceevidence at protein level
Length783
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesDDX21

GO terms

Show/Hide Table
GOName
GO:0001649 osteoblast differentiation
GO:0002735 positive regulation of myeloid dendritic cell cytokine production
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0006366 transcription by RNA polymerase II
GO:0016020 membrane
GO:0019843 rRNA binding
GO:0030515 snoRNA binding
GO:0035198 miRNA binding
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045815 positive regulation of gene expression, epigenetic
GO:0051607 defense response to virus
GO:0062176 R-loop disassembly
GO:0097322 7SK snRNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR012562 GUCTDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
DDX21_HUMANJUN_HUMANBioGRID, HPRD, MINT11823437 25609649 details
DDX21_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
DDX21_HUMANSRPK2_HUMANBioGRID, IntAct23602568 26167880 details
DDX21_HUMANIMA4_HUMANBioGRID, IntAct25416956 details
DDX21_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
DDX21_HUMANTERF2_HUMANbhf-ucl, BioGRID21044950 details
DDX21_HUMANDUX4_HUMANBioGRID, IntAct26816005 details
DDX21_HUMANTAU_HUMANIntAct32814053 details
DDX21_HUMANLITAF_HUMANIntAct32814053 details
DDX21_HUMANCARTF_HUMANIntAct32814053 details
DDX21_HUMANHD_HUMANIntAct32814053 details
DDX21_HUMANCALM1_HUMANBioGRID15840729 details
DDX21_HUMANCALM2_HUMANBioGRID15840729 details
DDX21_HUMANCALM3_HUMANBioGRID15840729 details
DDX21_HUMANH2AX_HUMANBioGRID23145133 details
DDX21_HUMANERG_HUMANBioGRID24591637 details
DDX21_HUMANUBC9_HUMANBioGRID19596686 details
DDX21_HUMANSUMO2_HUMANBioGRID19394292 details
DDX21_HUMANPTEN_HUMANBioGRID31685992 details
DDX21_HUMANNFKB2_HUMANIntAct14743216 details
DDX21_HUMANM3K14_HUMANIntAct14743216 details
DDX21_HUMANTF65_HUMANIntAct14743216 details
DDX21_HUMANTRAF6_HUMANIntAct17353931 details
DDX21_HUMANCRCM_HUMANIntAct17353931 details
DDX21_HUMANPINX1_HUMANIntAct17353931 details
DDX21_HUMANMRCKB_HUMANIntAct17353931 details
DDX21_HUMANHLAB_HUMANIntAct17353931 details
DDX21_HUMANIKKE_HUMANIntAct17353931 details
DDX21_HUMANSOMA_HUMANIntAct17353931 details
DDX21_HUMANAAKB1_HUMANIntAct17353931 details
DDX21_HUMANNOP56_HUMANBioGRID, IntAct12777385 26496610 34079125 details
DDX21_HUMANNPM_HUMANBioGRID, IntAct20431927 22939629 26186194 28514442 details
DDX21_HUMANXRN2_HUMANDIP25470060 details
DDX21_HUMANCDK9_HUMANBioGRID, DIP25470060 26209609 details
DDX21_HUMANLARP7_HUMANBioGRID, DIP25470060 26725010 29845934 details
DDX21_HUMANTAAR3_HUMANIntAct30021884 details
DDX21_HUMANSRRM2_HUMANBioGRID16159877 details
DDX21_HUMANSRRM1_HUMANBioGRID16159877 details
DDX21_HUMANCTBL1_HUMANBioGRID21385873 details
DDX21_HUMANDOT1L_HUMANBioGRID20431927 details
DDX21_HUMANAPTX_HUMANBioGRID15367657 details
DDX21_HUMAN1433E_HUMANBioGRID20462248 details
DDX21_HUMANITA4_HUMANBioGRID22623428 details
DDX21_HUMANAICDA_HUMANBioGRID23277564 details
DDX21_HUMANPA2G4_HUMANBioGRID19037095 details
DDX21_HUMANMACD1_HUMANBioGRID25735744 details
DDX21_HUMANU2AF2_HUMANBioGRID26641092 details
DDX21_HUMANCA131_HUMANBioGRID26472760 details
DDX21_HUMANRN168_HUMANBioGRID27558965 details
DDX21_HUMANPIAS1_HUMANHPRD9177271 details