Entity Details
| Primary name |
GTR9_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9NRM0 |
| EntryName | GTR9_HUMAN |
| FullName | Solute carrier family 2, facilitated glucose transporter member 9 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 540 |
| SequenceStatus | complete |
| DateCreated | 2001-11-16 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Apical cell membrane |
| Basolateral cell membrane |
Domains
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| Domain | Name | Category | Type |
| IPR003663 | Sugar/inositol transporter | Family | Family |
| IPR005828 | Major facilitator, sugar transporter-like | Family | Family |
| IPR005829 | Sugar transporter, conserved site | Site | Conserved site |
| IPR020846 | Major facilitator superfamily domain | Domain | Domain |
| IPR036259 | MFS transporter superfamily | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 612076 | OMIM | Hypouricemia renal 2 (RHUC2) | A disorder characterized by impaired uric acid reabsorption at the apical membrane of proximal renal tubule cells, and high urinary urate excretion. Patients often appear asymptomatic, but may be subject to exercise-induced acute renal failure, chronic renal dysfunction and nephrolithiasis. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00678 | Losartan | Drugbank | small molecule |
| DB01032 | Probenecid | Drugbank | small molecule |
| DB01914 | D-glucose | Swissprot | small molecule |
| DB08844 | Uric acid | Swissprot | small molecule |
| DB09341 | Dextrose, unspecified form | Swissprot | small molecule |
| DB09502 | Fludeoxyglucose (18F) | Swissprot | small molecule |
Interactions
2 interactions