Entity Details

Primary name AT8A2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NTI2
EntryNameAT8A2_HUMAN
FullNamePhospholipid-transporting ATPase IB
TaxID9606
Evidenceevidence at protein level
Length1188
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesATP8A2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0003011 involuntary skeletal muscle contraction
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0007409 axonogenesis
GO:0007568 aging
GO:0008285 negative regulation of cell population proliferation
GO:0010842 retina layer formation
GO:0010976 positive regulation of neuron projection development
GO:0010996 response to auditory stimulus
GO:0016021 integral component of membrane
GO:0016887 ATP hydrolysis activity
GO:0040018 positive regulation of multicellular organism growth
GO:0042472 inner ear morphogenesis
GO:0042755 eating behavior
GO:0043588 skin development
GO:0045332 phospholipid translocation
GO:0048666 neuron development
GO:0050884 neuromuscular process controlling posture
GO:0050908 detection of light stimulus involved in visual perception
GO:0060052 neurofilament cytoskeleton organization
GO:0061092 positive regulation of phospholipid translocation
GO:0090555 phosphatidylethanolamine flippase activity
GO:0140326 ATPase-coupled intramembrane lipid transporter activity
GO:0140331 aminophospholipid translocation
GO:0140346 phosphatidylserine flippase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Endosome
Golgi apparatus
Membrane
Photoreceptor inner segment

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR006539 P-type ATPase, subfamily IVFamilyFamily
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR032630 P-type ATPase, C-terminalDomainDomain
IPR032631 P-type ATPase, N-terminalDomainDomain
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AT8A2_HUMANUIMC1_HUMANBioGRID17621610 details
AT8A2_HUMANCC50A_HUMANUniProt20947505 details