Entity Details

Primary name TGM5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43548
EntryNameTGM5_HUMAN
FullNameProtein-glutamine gamma-glutamyltransferase 5
TaxID9606
Evidenceevidence at protein level
Length720
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesTGM5

GO terms

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GOName
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006464 cellular protein modification process
GO:0008544 epidermis development
GO:0018149 peptide cross-linking
GO:0046872 metal ion binding
GO:0070268 cornification

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001102 Transglutaminase, N-terminalDomainDomain
IPR002931 Transglutaminase-likeDomainDomain
IPR008958 Transglutaminase, C-terminalDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR013808 Transglutaminase, active siteSiteActive site
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR023608 Protein-glutamine gamma-glutamyltransferase, animalFamilyFamily
IPR036238 Transglutaminase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR036985 Transglutaminase-like superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00130 L-GlutamineDrugbanksmall molecule