Entity Details

Primary name LCMT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UIC8
EntryNameLCMT1_HUMAN
FullNameLeucine carboxyl methyltransferase 1
TaxID9606
Evidenceevidence at protein level
Length334
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesLCMT1

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0003880 protein C-terminal carboxyl O-methyltransferase activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006464 cellular protein modification process
GO:0006479 protein methylation
GO:0006481 C-terminal protein methylation
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0010906 regulation of glucose metabolic process
GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity
GO:0031333 negative regulation of protein-containing complex assembly
GO:0042981 regulation of apoptotic process
GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint

Subcellular Location

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Domains

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DomainNameCategoryType
IPR007213 Methyltransferase Ppm1/Ppm2/TcmpFamilyFamily
IPR016651 Leucine carboxyl methyltransferase 1FamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00149 LeucineDrugbanksmall molecule

Interactions

4 interactions