Entity Details

Primary name HERC5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UII4
EntryNameHERC5_HUMAN
FullNameE3 ISG15--protein ligase HERC5
TaxID9606
Evidenceevidence at protein level
Length1024
SequenceStatuscomplete
DateCreated2004-05-10
DateModified2021-06-02

Ontological Relatives

GenesHERC5

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000209 protein polyubiquitination
GO:0003723 RNA binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016567 protein ubiquitination
GO:0032020 ISG15-protein conjugation
GO:0032480 negative regulation of type I interferon production
GO:0042296 ISG15 transferase activity
GO:0045087 innate immune response
GO:0048471 perinuclear region of cytoplasm
GO:0050688 regulation of defense response to virus
GO:0051607 defense response to virus
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000408 Regulator of chromosome condensation, RCC1RepeatRepeat
IPR000569 HECT domainDomainDomain
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIFamilyHomologous superfamily
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily

Diseases

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