Entity Details

Primary name TAOK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UL54
EntryNameTAOK2_HUMAN
FullNameSerine/threonine-protein kinase TAO2
TaxID9606
Evidenceevidence at protein level
Length1235
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesTAOK2

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0000187 obsolete activation of MAPK activity
GO:0001558 regulation of cell growth
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006612 protein targeting to membrane
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0007257 obsolete activation of JUN kinase activity
GO:0007409 axonogenesis
GO:0008360 regulation of cell shape
GO:0015629 actin cytoskeleton
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0030036 actin cytoskeleton organization
GO:0030424 axon
GO:0030659 cytoplasmic vesicle membrane
GO:0031098 stress-activated protein kinase signaling cascade
GO:0031410 cytoplasmic vesicle
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031954 positive regulation of protein autophosphorylation
GO:0032147 activation of protein kinase activity
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0032956 regulation of actin cytoskeleton organization
GO:0038191 neuropilin binding
GO:0043005 neuron projection
GO:0043235 receptor complex
GO:0044294 dendritic growth cone
GO:0044295 axonal growth cone
GO:0046330 positive regulation of JNK cascade
GO:0046777 protein autophosphorylation
GO:0048041 focal adhesion assembly
GO:0048156 tau protein binding
GO:0048812 neuron projection morphogenesis
GO:0050321 tau-protein kinase activity
GO:0051403 stress-activated MAPK cascade
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0150019 basal dendrite morphogenesis
GO:0150020 basal dendrite arborization

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Cytoplasmic vesicle membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB04522 DexfosfoserineDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule