Entity Details

Primary name TLN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4G6
EntryNameTLN2_HUMAN
FullNameTalin-2
TaxID9606
Evidenceevidence at protein level
Length2542
SequenceStatuscomplete
DateCreated2002-10-25
DateModified2021-06-02

Ontological Relatives

GenesTLN2

GO terms

Show/Hide Table
GOName
GO:0001726 ruffle
GO:0003779 actin binding
GO:0005178 integrin binding
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007043 cell-cell junction assembly
GO:0007155 cell adhesion
GO:0015629 actin cytoskeleton
GO:0045202 synapse
GO:0051015 actin filament binding
GO:0098609 cell-cell adhesion

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR002558 I/LWEQ domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR015009 Vinculin-binding site-containing domainDomainDomain
IPR015224 Talin, centralDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR032425 Talin, N-terminal F0 domainDomainDomain
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR035964 I/LWEQ domain superfamilyFamilyHomologous superfamily
IPR036476 Talin, central domain superfamilyFamilyHomologous superfamily
IPR036723 Alpha-catenin/vinculin-like superfamilyFamilyHomologous superfamily
IPR037438 Talin-1/2, rod-segmentDomainDomain

Diseases

Show/Hide Table