Entity Details

Primary name TIM8A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60220
EntryNameTIM8A_HUMAN
FullNameMitochondrial import inner membrane translocase subunit Tim8 A
TaxID9606
Evidenceevidence at protein level
Length97
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesTIMM8A

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0007399 nervous system development
GO:0042802 identical protein binding
GO:0045039 protein insertion into mitochondrial inner membrane
GO:0046872 metal ion binding
GO:0072321 obsolete chaperone-mediated protein transport

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR004217 Tim10-likeDomainDomain
IPR035427 Tim10-like domain superfamilyFamilyHomologous superfamily
IPR039238 Mitochondrial import inner membrane translocase subunit Tim8/13FamilyFamily

Diseases

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Disease IDSourceNameDescription
304700 OMIMMohr-Tranebjaerg syndrome (MTS)An X-linked recessive disorder characterized by postlingual sensorineural deafness with onset in early childhood, dystonia, spasticity, dysphagia, mental deterioration, paranoia and cortical blindness. The disease is caused by variants affecting the gene represented in this entry.