Entity Details

Primary name NSMA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60906
EntryNameNSMA_HUMAN
FullNameSphingomyelin phosphodiesterase 2
TaxID9606
Evidenceevidence at protein level
Length423
SequenceStatuscomplete
DateCreated2002-02-11
DateModified2021-06-02

Ontological Relatives

GenesSMPD2

GO terms

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GOName
GO:0004620 phospholipase activity
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0006684 sphingomyelin metabolic process
GO:0006685 sphingomyelin catabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0009612 response to mechanical stimulus
GO:0016020 membrane
GO:0030149 sphingolipid catabolic process
GO:0035556 intracellular signal transduction
GO:0046513 ceramide biosynthetic process
GO:0046872 metal ion binding
GO:0071944 cell periphery
GO:2000304 positive regulation of ceramide biosynthetic process

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily
IPR038772 Sphingomyelin phosphodiesterase 2-likeFamilyFamily

Diseases

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