Entity Details

Primary name CATL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60911
EntryNameCATL2_HUMAN
FullNameCathepsin L2
TaxID9606
Evidenceevidence at protein level
Length334
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesCTSV

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0006955 immune response
GO:0008234 cysteine-type peptidase activity
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022617 extracellular matrix disassembly
GO:0043202 lysosomal lumen
GO:0045616 regulation of keratinocyte differentiation
GO:0051603 proteolysis involved in cellular protein catabolic process

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR000668 Peptidase C1A, papain C-terminalDomainDomain
IPR013201 Cathepsin propeptide inhibitor domain (I29)DomainDomain
IPR025660 Cysteine peptidase, histidine active siteSiteActive site
IPR025661 Cysteine peptidase, asparagine active siteSiteActive site
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily
IPR039417 Papain-like cysteine endopeptidaseDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02869 3-amino-5-phenylpentaneDrugbanksmall molecule
DB04451 4-Methylpiperazin-1-Yl Carbonyl GroupDrugbanksmall molecule