Entity Details

Primary name PITX3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75364
EntryNamePITX3_HUMAN
FullNamePituitary homeobox 3
TaxID9606
Evidenceevidence at protein level
Length302
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPITX3

GO terms

Show/Hide Table
GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002088 lens development in camera-type eye
GO:0002089 lens morphogenesis in camera-type eye
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007568 aging
GO:0007626 locomotory behavior
GO:0009653 anatomical structure morphogenesis
GO:0009887 animal organ morphogenesis
GO:0014014 negative regulation of gliogenesis
GO:0030901 midbrain development
GO:0035902 response to immobilization stress
GO:0042220 response to cocaine
GO:0043025 neuronal cell body
GO:0043278 response to morphine
GO:0043525 positive regulation of neuron apoptotic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048666 neuron development
GO:0070306 lens fiber cell differentiation
GO:0071542 dopaminergic neuron differentiation
GO:1904313 response to methamphetamine hydrochloride
GO:1904935 positive regulation of cell proliferation in midbrain
GO:1990792 cellular response to glial cell derived neurotrophic factor
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003654 OAR domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR016233 Homeobox protein Pitx/unc30FamilyFamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

Show/Hide Table

Interactions

4 interactions