Entity Details

Primary name RECK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95980
EntryNameRECK_HUMAN
FullNameReversion-inducing cysteine-rich protein with Kazal motifs
TaxID9606
Evidenceevidence at protein level
Length971
SequenceStatuscomplete
DateCreated2002-04-16
DateModified2021-06-02

Ontological Relatives

GenesRECK

GO terms

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GOName
GO:0001955 blood vessel maturation
GO:0002040 sprouting angiogenesis
GO:0004866 endopeptidase inhibitor activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007566 embryo implantation
GO:0008191 metalloendopeptidase inhibitor activity
GO:0016020 membrane
GO:0017147 Wnt-protein binding
GO:0030198 extracellular matrix organization
GO:0030336 negative regulation of cell migration
GO:0031225 anchored component of membrane
GO:0035115 embryonic forelimb morphogenesis
GO:0045765 regulation of angiogenesis
GO:0090210 regulation of establishment of blood-brain barrier
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1904684 negative regulation of metalloendopeptidase activity
GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway
GO:1990909 Wnt signalosome

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002350 Kazal domainDomainDomain
IPR036058 Kazal domain superfamilyFamilyHomologous superfamily
IPR039016 Reversion-inducing cysteine-rich protein with Kazal motifsFamilyFamily

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
RECK_HUMANTRI69_HUMANBioGRID, MINT21516116 25416956 32296183 details
RECK_HUMANMTR1B_HUMANBioGRID, IntAct26514267 details
RECK_HUMANTEKT4_HUMANBioGRID, IntAct25416956 31515488 32296183 details
RECK_HUMANCGL_HUMANBioGRID25416956 32296183 details
RECK_HUMANMEOX2_HUMANBioGRID25416956 32296183 details
RECK_HUMANREL_HUMANBioGRID25416956 details
RECK_HUMANITF2_HUMANBioGRID25416956 32296183 details
RECK_HUMANKEAP1_HUMANBioGRID25416956 32296183 details
RECK_HUMANTRI39_HUMANBioGRID25416956 details
RECK_HUMANUSBP1_HUMANBioGRID25416956 details
RECK_HUMANK1C40_HUMANBioGRID25416956 details
RECK_HUMANNT2NC_HUMANBioGRID25416956 32296183 details
RECK_HUMANNT2NA_HUMANBioGRID25416956 32296183 details
RECK_HUMANCEP44_HUMANBioGRID21516116 details
RECK_HUMANKLH20_HUMANBioGRID32296183 details
RECK_HUMANNDUB7_HUMANBioGRID32296183 details
RECK_HUMANBMF_HUMANBioGRID32296183 details
RECK_HUMANGLRX3_HUMANBioGRID32296183 details
RECK_HUMANSPSB2_HUMANBioGRID32296183 details
RECK_HUMANMELPH_HUMANBioGRID32296183 details
RECK_HUMANNR4A3_HUMANBioGRID32296183 details
RECK_HUMANPROP_HUMANBioGRID32296183 details
RECK_HUMANCTIF_HUMANBioGRID32296183 details
RECK_HUMANCCN3_HUMANBioGRID32296183 details
RECK_HUMANPRI2_HUMANBioGRID32296183 details
RECK_HUMANSRB4D_HUMANBioGRID32296183 details
RECK_HUMANADA12_HUMANBioGRID32296183 details
RECK_HUMANLCN1_HUMANBioGRID32296183 details
RECK_HUMANOXER1_HUMANBioGRID32296183 details
RECK_HUMANDISC1_HUMANBioGRID32296183 details
RECK_HUMANZN704_HUMANBioGRID32296183 details
RECK_HUMANTIRR_HUMANBioGRID32296183 details
RECK_HUMANKR132_HUMANBioGRID32296183 details
RECK_HUMANZN438_HUMANBioGRID32296183 details
RECK_HUMANEFHC2_HUMANBioGRID32296183 details
RECK_HUMANKR108_HUMANBioGRID32296183 details
RECK_HUMANINCA1_HUMANBioGRID32296183 details
RECK_HUMANCRTP1_HUMANBioGRID32296183 details
RECK_HUMANKR261_HUMANBioGRID32296183 details
RECK_HUMANKRA31_HUMANBioGRID32296183 details
RECK_HUMANCV039_HUMANBioGRID32296183 details
RECK_HUMANERBB2_HUMANMINT21255571 details
RECK_HUMANMMP9_HUMANHPRD9789069 details