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Entity Details
Primary name
C1QA_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P02745
EntryName
C1QA_HUMAN
FullName
Complement C1q subcomponent subunit A
TaxID
9606
Evidence
evidence at protein level
Length
245
SequenceStatus
complete
DateCreated
1986-07-21
DateModified
2021-06-02
Ontological Relatives
Genes
C1QA
GO terms
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GO
Name
GO:0001540
amyloid-beta binding
GO:0001774
microglial cell activation
GO:0005576
extracellular region
GO:0005581
collagen trimer
GO:0005602
complement component C1 complex
GO:0006956
complement activation
GO:0006958
complement activation, classical pathway
GO:0007267
cell-cell signaling
GO:0007568
aging
GO:0010039
response to iron ion
GO:0016032
viral process
GO:0016322
neuron remodeling
GO:0030449
regulation of complement activation
GO:0045087
innate immune response
GO:0045202
synapse
GO:0048143
astrocyte activation
GO:0050808
synapse organization
GO:0062023
collagen-containing extracellular matrix
GO:0098794
postsynapse
GO:0098883
synapse pruning
GO:0150062
complement-mediated synapse pruning
GO:0150064
vertebrate eye-specific patterning
GO:1901216
positive regulation of neuron death
Subcellular Location
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Subcellular Location
Secreted
Domains
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Domain
Name
Category
Type
IPR001073
C1q domain
Domain
Domain
IPR008160
Collagen triple helix repeat
Repeat
Repeat
IPR008983
Tumour necrosis factor-like domain superfamily
Family
Homologous superfamily
IPR037572
Complement C1q subcomponent subunit A
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB00002
Cetuximab
Drugbank
biotech
DB00005
Etanercept
Drugbank
biotech
DB00110
Palivizumab
Drugbank
biotech
DB00111
Daclizumab
Drugbank
biotech
DB00112
Bevacizumab
Drugbank
biotech
Interactions
31 interactions
Interactor
Partner
Sources
Publications
Link
C1QA_HUMAN
HIPK3_HUMAN
BioGRID, HPRD, MINT
15231748
details
C1QA_HUMAN
C1QB_HUMAN
HPRD, IntAct, MINT
12960167
21054788
7240
details
C1QA_HUMAN
PIAS2_HUMAN
BioGRID, IntAct
21988832
details
C1QA_HUMAN
GNA1_HUMAN
BioGRID, IntAct
21988832
details
C1QA_HUMAN
SGTA_HUMAN
BioGRID, IntAct
21988832
details
C1QA_HUMAN
BAG6_HUMAN
BioGRID, IntAct
21988832
details
C1QA_HUMAN
UBQL1_HUMAN
BioGRID, IntAct
21988832
details
C1QA_HUMAN
UBQL2_HUMAN
BioGRID, IntAct
21988832
32296183
details
C1QA_HUMAN
S2547_HUMAN
BioGRID, IntAct
21988832
details
C1QA_HUMAN
PP1G_HUMAN
BioGRID, IntAct
21382349
23080069
details
C1QA_HUMAN
PP1A_HUMAN
BioGRID, IntAct
22321011
details
C1QA_HUMAN
SGTB_HUMAN
BioGRID, IntAct
32296183
details
C1QA_HUMAN
HSPB2_HUMAN
bhf-ucl, BioGRID
26465331
details
C1QA_HUMAN
NLGN3_HUMAN
BioGRID, IntAct
25464930
details
C1QA_HUMAN
HMGB1_HUMAN
UniProt
32867128
details
C1QA_HUMAN
CRP_HUMAN
BioGRID
10490997
details
C1QA_HUMAN
PGS2_HUMAN
BioGRID, HPRD
1431141
details
C1QA_HUMAN
FINC_HUMAN
BioGRID, HPRD
6981115
details
C1QA_HUMAN
BMP1_HUMAN
IntAct
29209066
details
C1QA_HUMAN
C1S_HUMAN
BioGRID, HPRD
10878362
details
C1QA_HUMAN
C1R_HUMAN
BioGRID, HPRD
10878362
2372546
details
C1QA_HUMAN
RAC1_HUMAN
BioGRID
25301945
details
C1QA_HUMAN
SFTA1_HUMAN
HPRD
11714829
details
C1QA_HUMAN
C1QBP_HUMAN
HPRD
8195709
details
C1QA_HUMAN
CO2A1_HUMAN
HPRD
8778019
details
C1QA_HUMAN
C1QR1_HUMAN
HPRD
9476117
details
C1QA_HUMAN
CR1_HUMAN
HPRD
10528211
details
C1QA_HUMAN
HRG_HUMAN
HPRD
9184145
details
C1QA_HUMAN
CSPG4_HUMAN
HPRD
9013976
details
C1QA_HUMAN
PTX3_HUMAN
HPRD
12645945
details
C1QA_HUMAN
SAMP_HUMAN
HPRD
8417122
details
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