Entity Details

Primary name TDT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04053
EntryNameTDT_HUMAN
FullNameDNA nucleotidylexotransferase
TaxID9606
Evidenceevidence at protein level
Length509
SequenceStatuscomplete
DateCreated1986-11-01
DateModified2021-06-02

Ontological Relatives

GenesDNTT

GO terms

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GOName
GO:0000791 euchromatin
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0003912 DNA nucleotidylexotransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006259 DNA metabolic process
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006304 DNA modification
GO:0016363 nuclear matrix
GO:0033198 response to ATP
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001357 BRCT domainDomainDomain
IPR001726 DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase muFamilyFamily
IPR002054 DNA-directed DNA polymerase XDomainDomain
IPR010996 DNA polymerase beta-like, N-terminal domainDomainDomain
IPR018944 DNA polymerase lambda, fingers domainDomainDomain
IPR019843 DNA polymerase family X, binding siteSiteBinding site
IPR022312 DNA polymerase family XFamilyFamily
IPR027292 DNA nucleotidylexotransferase (TdT)FamilyFamily
IPR027421 DNA polymerase lambda lyase domain superfamilyFamilyHomologous superfamily
IPR028207 DNA polymerase beta, palm domainDomainDomain
IPR029398 DNA polymerase beta, thumb domainDomainDomain
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily
IPR037160 DNA polymerase, thumb domain superfamilyFamilyHomologous superfamily
IPR043519 Nucleotidyltransferase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02189 2',3'-Dideoxyadenosine triphosphateDrugbanksmall molecule