Entity Details

Primary name OPSD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08100
EntryNameOPSD_HUMAN
FullNameRhodopsin
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesRHO

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001523 retinoid metabolic process
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0004930 G protein-coupled receptor activity
GO:0005502 11-cis retinal binding
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007601 visual perception
GO:0007602 phototransduction
GO:0007603 phototransduction, visible light
GO:0008020 G protein-coupled photoreceptor activity
GO:0016021 integral component of membrane
GO:0016038 absorption of visible light
GO:0016056 rhodopsin mediated signaling pathway
GO:0018298 protein-chromophore linkage
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0030660 Golgi-associated vesicle membrane
GO:0042622 photoreceptor outer segment membrane
GO:0043052 thermotaxis
GO:0045494 photoreceptor cell maintenance
GO:0046872 metal ion binding
GO:0050960 detection of temperature stimulus involved in thermoception
GO:0060041 retina development in camera-type eye
GO:0060170 ciliary membrane
GO:0060271 cilium assembly
GO:0060342 photoreceptor inner segment membrane
GO:0071482 cellular response to light stimulus
GO:0097225 sperm midpiece
GO:0097381 photoreceptor disc membrane
GO:1990913 sperm head plasma membrane

Subcellular Location

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Subcellular Location
Cell projection
Membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000732 RhodopsinFamilyFamily
IPR001760 OpsinFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR019477 Rhodopsin, N-terminalDomainDomain
IPR027430 Visual pigments (opsins) retinal binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB01159 HalothaneDrugbanksmall molecule
DB01646 N-AcetylmethionineDrugbanksmall molecule
DB01728 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamineDrugbanksmall molecule
DB02451 B-nonylglucosideDrugbanksmall molecule
DB02482 PhosphonothreonineDrugbanksmall molecule
DB03152 B-2-OctylglucosideDrugbanksmall molecule
DB03381 HexadecanalDrugbanksmall molecule
DB03796 Palmitic AcidDrugbanksmall molecule
DB04079 Heptane-1,2,3-TriolDrugbanksmall molecule
DB04147 Dodecyldimethylamine N-oxideDrugbanksmall molecule
DB04233 (Hydroxyethyloxy)Tri(Ethyloxy)OctaneDrugbanksmall molecule
DB04450 Heptyl 1-ThiohexopyranosideDrugbanksmall molecule
DB04522 DexfosfoserineDrugbanksmall molecule