Entity Details

Primary name CD3G_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09693
EntryNameCD3G_HUMAN
FullNameT-cell surface glycoprotein CD3 gamma chain
TaxID9606
Evidenceevidence at protein level
Length182
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesCD3G

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004888 transmembrane signaling receptor activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007163 establishment or maintenance of cell polarity
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0015031 protein transport
GO:0018149 peptide cross-linking
GO:0030159 signaling receptor complex adaptor activity
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042101 T cell receptor complex
GO:0042105 alpha-beta T cell receptor complex
GO:0042110 T cell activation
GO:0042608 T cell receptor binding
GO:0042802 identical protein binding
GO:0045059 positive thymic T cell selection
GO:0046982 protein heterodimerization activity
GO:0050776 regulation of immune response
GO:0050852 T cell receptor signaling pathway
GO:0061024 membrane organization
GO:0065003 protein-containing complex assembly
GO:0070228 regulation of lymphocyte apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003110 Phosphorylated immunoreceptor signalling ITAMRepeatRepeat
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015484 CD3 protein, epsilon/gamma/delta subunitFamilyFamily
IPR032052 CD3 gamma/delta subunit, Ig-like domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00075 MuromonabDrugbankbiotech