Entity Details

Primary name TPR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12270
EntryNameTPR_HUMAN
FullNameNucleoprotein TPR
TaxID9606
Evidenceevidence at protein level
Length2363
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesTPR

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000776 kinetochore
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005868 cytoplasmic dynein complex
GO:0006110 regulation of glycolytic process
GO:0006404 RNA import into nucleus
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0006409 tRNA export from nucleus
GO:0006606 protein import into nucleus
GO:0006999 nuclear pore organization
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0010965 regulation of mitotic sister chromatid separation
GO:0015631 tubulin binding
GO:0016032 viral process
GO:0016925 protein sumoylation
GO:0017056 structural constituent of nuclear pore
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0019898 extrinsic component of membrane
GO:0031072 heat shock protein binding
GO:0031453 positive regulation of heterochromatin assembly
GO:0031965 nuclear membrane
GO:0031990 mRNA export from nucleus in response to heat stress
GO:0032880 regulation of protein localization
GO:0034399 nuclear periphery
GO:0034605 cellular response to heat
GO:0035457 cellular response to interferon-alpha
GO:0042307 positive regulation of protein import into nucleus
GO:0042405 nuclear inclusion body
GO:0042803 protein homodimerization activity
GO:0043657 host cell
GO:0044615 nuclear pore nuclear basket
GO:0045947 negative regulation of translational initiation
GO:0046827 positive regulation of protein export from nucleus
GO:0046832 negative regulation of RNA export from nucleus
GO:0051019 mitogen-activated protein kinase binding
GO:0051301 cell division
GO:0060964 regulation of gene silencing by miRNA
GO:0070840 dynein complex binding
GO:0070849 response to epidermal growth factor
GO:0072686 mitotic spindle
GO:0075733 intracellular transport of virus
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:0090316 positive regulation of intracellular protein transport
GO:1900034 regulation of cellular response to heat
GO:1901673 regulation of mitotic spindle assembly

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus
Nucleus envelope
Nucleus membrane

Domains

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DomainNameCategoryType
IPR012929 Nucleoprotein TPR/MLP1DomainDomain

Diseases

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