Entity Details

Primary name EDN3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14138
EntryNameEDN3_HUMAN
FullNameEndothelin-3
TaxID9606
Evidenceevidence at protein level
Length238
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesEDN3

GO terms

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GOName
GO:0001755 neural crest cell migration
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0003100 regulation of systemic arterial blood pressure by endothelin
GO:0005102 signaling receptor binding
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006874 cellular calcium ion homeostasis
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007275 multicellular organism development
GO:0008015 blood circulation
GO:0008284 positive regulation of cell population proliferation
GO:0010460 positive regulation of heart rate
GO:0010468 regulation of gene expression
GO:0010961 cellular magnesium ion homeostasis
GO:0014826 vein smooth muscle contraction
GO:0019229 regulation of vasoconstriction
GO:0030072 peptide hormone secretion
GO:0030182 neuron differentiation
GO:0030318 melanocyte differentiation
GO:0030593 neutrophil chemotaxis
GO:0031708 endothelin B receptor binding
GO:0042310 vasoconstriction
GO:0043406 positive regulation of MAP kinase activity
GO:0045597 positive regulation of cell differentiation
GO:0045840 positive regulation of mitotic nuclear division
GO:0046887 positive regulation of hormone secretion
GO:0048016 inositol phosphate-mediated signaling
GO:0048070 regulation of developmental pigmentation
GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity
GO:1901381 positive regulation of potassium ion transmembrane transport

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001928 Endothelin-like toxinDomainDomain
IPR019764 Endothelin-like toxin, conserved siteSiteConserved site
IPR020475 EndothelinFamilyFamily

Diseases

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