Entity Details

Primary name INGR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15260
EntryNameINGR1_HUMAN
FullNameInterferon gamma receptor 1
TaxID9606
Evidenceevidence at protein level
Length489
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesIFNGR1

GO terms

Show/Hide Table
GOName
GO:0001774 microglial cell activation
GO:0004896 cytokine receptor activity
GO:0004906 interferon-gamma receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0009615 response to virus
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032760 positive regulation of tumor necrosis factor production
GO:0048143 astrocyte activation
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060334 regulation of interferon-gamma-mediated signaling pathway
GO:1900222 negative regulation of amyloid-beta clearance
GO:1902004 positive regulation of amyloid-beta formation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003961 Fibronectin type IIIDomainDomain
IPR008355 Interferon gamma receptor alpha subunitFamilyFamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR021126 Interferon gamma receptor, poxvirus/mammalDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00033 Interferon gamma-1bDrugbankbiotech