Entity Details

Primary name C5AR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21730
EntryNameC5AR1_HUMAN
FullNameC5a anaphylatoxin chemotactic receptor 1
TaxID9606
Evidenceevidence at protein level
Length350
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesC5AR1

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001774 microglial cell activation
GO:0001856 complement component C5a binding
GO:0002430 complement receptor mediated signaling pathway
GO:0004875 complement receptor activity
GO:0004878 complement component C5a receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007606 sensory perception of chemical stimulus
GO:0009986 cell surface
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010759 positive regulation of macrophage chemotaxis
GO:0016323 basolateral plasma membrane
GO:0021534 cell proliferation in hindbrain
GO:0030449 regulation of complement activation
GO:0030593 neutrophil chemotaxis
GO:0030667 secretory granule membrane
GO:0031100 animal organ regeneration
GO:0032494 response to peptidoglycan
GO:0032496 response to lipopolysaccharide
GO:0038178 complement component C5a signaling pathway
GO:0042789 mRNA transcription by RNA polymerase II
GO:0043312 neutrophil degranulation
GO:0043524 negative regulation of neuron apoptotic process
GO:0045177 apical part of cell
GO:0045766 positive regulation of angiogenesis
GO:0048143 astrocyte activation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050830 defense response to Gram-positive bacterium
GO:0050890 cognition
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0097242 amyloid-beta clearance
GO:0099172 presynapse organization
GO:1902947 regulation of tau-protein kinase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000826 Formyl peptide receptor-relatedFamilyFamily
IPR001274 C5a1/C5a2 anaphylatoxin chemotactic receptorFamilyFamily
IPR002234 Anaphylatoxin chemotactic receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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