Entity Details

Primary name BMP6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22004
EntryNameBMP6_HUMAN
FullNameBone morphogenetic protein 6
TaxID9606
Evidenceevidence at protein level
Length513
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesBMP6

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001501 skeletal system development
GO:0001649 osteoblast differentiation
GO:0001654 eye development
GO:0001822 kidney development
GO:0001938 positive regulation of endothelial cell proliferation
GO:0001958 endochondral ossification
GO:0003323 type B pancreatic cell development
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006879 cellular iron ion homeostasis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0014823 response to activity
GO:0030501 positive regulation of bone mineralization
GO:0030509 BMP signaling pathway
GO:0030539 male genitalia development
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0031982 vesicle
GO:0032026 response to magnesium ion
GO:0032332 positive regulation of chondrocyte differentiation
GO:0032349 positive regulation of aldosterone biosynthetic process
GO:0032526 response to retinoic acid
GO:0043117 positive regulation of vascular permeability
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050714 positive regulation of protein secretion
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051216 cartilage development
GO:0051384 response to glucocorticoid
GO:0060391 positive regulation of SMAD protein signal transduction
GO:0060395 SMAD protein signal transduction
GO:0060586 multicellular organismal iron ion homeostasis
GO:0070700 BMP receptor binding
GO:0071260 cellular response to mechanical stimulus
GO:0071281 cellular response to iron ion
GO:0071773 cellular response to BMP stimulus
GO:1903392 negative regulation of adherens junction organization
GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin
GO:2000860 positive regulation of aldosterone secretion

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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