Entity Details

Primary name GCSP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23378
EntryNameGCSP_HUMAN
FullNameGlycine dehydrogenase (decarboxylating), mitochondrial
TaxID9606
Evidenceevidence at protein level
Length1020
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesGLDC

GO terms

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GOName
GO:0004375 glycine dehydrogenase (decarboxylating) activity
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005886 plasma membrane
GO:0005960 glycine cleavage complex
GO:0006546 glycine catabolic process
GO:0009055 electron transfer activity
GO:0016594 glycine binding
GO:0016829 lyase activity
GO:0019464 glycine decarboxylation via glycine cleavage system
GO:0019899 enzyme binding
GO:0030170 pyridoxal phosphate binding
GO:0036255 response to methylamine
GO:0042803 protein homodimerization activity
GO:0065003 protein-containing complex assembly
GO:0070280 pyridoxal binding
GO:1903442 response to lipoic acid

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolaseDomainDomain
IPR003437 Glycine dehydrogenase (decarboxylating)FamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily
IPR020581 Glycine cleavage system P proteinFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00145 GlycineDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GCSP_HUMANTLR10_HUMANHPRD16482509 details
GCSP_HUMANGCSP_HUMANBioGRID, HPRD6778858 details