Entity Details

Primary name FPR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP25090
EntryNameFPR2_HUMAN
FullNameN-formyl peptide receptor 2
TaxID9606
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesFPR2

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001774 microglial cell activation
GO:0001934 positive regulation of protein phosphorylation
GO:0002430 complement receptor mediated signaling pathway
GO:0002768 immune response-regulating cell surface receptor signaling pathway
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004982 N-formyl peptide receptor activity
GO:0005124 scavenger receptor binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0016021 integral component of membrane
GO:0019722 calcium-mediated signaling
GO:0032930 positive regulation of superoxide anion generation
GO:0035579 specific granule membrane
GO:0038023 signaling receptor activity
GO:0038024 cargo receptor activity
GO:0042742 defense response to bacterium
GO:0043312 neutrophil degranulation
GO:0045089 positive regulation of innate immune response
GO:0048143 astrocyte activation
GO:0050728 negative regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
GO:0050918 positive chemotaxis
GO:0061903 positive regulation of 1-phosphatidylinositol-3-kinase activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070821 tertiary granule membrane
GO:0090026 positive regulation of monocyte chemotaxis
GO:0101003 ficolin-1-rich granule membrane
GO:1904646 cellular response to amyloid-beta

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000826 Formyl peptide receptor-relatedFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR027345 Formyl peptide receptor 1/2FamilyFamily

Diseases

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