Entity Details

Primary name ITB8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26012
EntryNameITB8_HUMAN
FullNameIntegrin beta-8
TaxID9606
Evidenceevidence at protein level
Length769
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesITGB8

GO terms

Show/Hide Table
GOName
GO:0001570 vasculogenesis
GO:0001573 ganglioside metabolic process
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008305 integrin complex
GO:0009615 response to virus
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016477 cell migration
GO:0030198 extracellular matrix organization
GO:0033627 cell adhesion mediated by integrin
GO:0034686 integrin alphav-beta8 complex
GO:0038023 signaling receptor activity
GO:0045766 positive regulation of angiogenesis
GO:0051216 cartilage development
GO:0060022 hard palate development
GO:0060674 placenta blood vessel development
GO:0061520 Langerhans cell differentiation
GO:0070062 extracellular exosome
GO:1901388 regulation of transforming growth factor beta activation
GO:1990430 extracellular matrix protein binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR002369 Integrin beta subunit, VWA domainDomainDomain
IPR013111 EGF-like domain, extracellularDomainDomain
IPR015442 Integrin beta-8 subunitFamilyFamily
IPR015812 Integrin beta subunitFamilyFamily
IPR016201 PSI domainDomainDomain
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily
IPR033760 Integrin beta N-terminalDomainDomain
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions