Entity Details

Primary name OXYR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30559
EntryNameOXYR_HUMAN
FullNameOxytocin receptor
TaxID9606
Evidenceevidence at protein level
Length389
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesOXTR

GO terms

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GOName
GO:0001967 suckling behavior
GO:0001975 response to amphetamine
GO:0001992 regulation of systemic arterial blood pressure by vasopressin
GO:0004930 G protein-coupled receptor activity
GO:0004990 oxytocin receptor activity
GO:0005000 vasopressin receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0005912 adherens junction
GO:0006936 muscle contraction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007507 heart development
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0007613 memory
GO:0010701 positive regulation of norepinephrine secretion
GO:0016324 apical plasma membrane
GO:0017046 peptide hormone binding
GO:0021537 telencephalon development
GO:0030431 sleep
GO:0032230 positive regulation of synaptic transmission, GABAergic
GO:0032355 response to estradiol
GO:0032570 response to progesterone
GO:0034059 response to anoxia
GO:0034097 response to cytokine
GO:0035176 social behavior
GO:0042220 response to cocaine
GO:0042277 peptide binding
GO:0042493 response to drug
GO:0042711 maternal behavior
GO:0042713 sperm ejaculation
GO:0042755 eating behavior
GO:0043434 response to peptide hormone
GO:0044849 estrous cycle
GO:0045777 positive regulation of blood pressure
GO:0045907 positive regulation of vasoconstriction
GO:0048565 digestive tract development
GO:0051965 positive regulation of synapse assembly
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060137 maternal process involved in parturition
GO:0060406 positive regulation of penile erection
GO:0060455 negative regulation of gastric acid secretion
GO:0070371 ERK1 and ERK2 cascade
GO:0070474 positive regulation of uterine smooth muscle contraction
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001817 Vasopressin receptorFamilyFamily
IPR002062 Oxytocin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00107 OxytocinDrugbankbiotech
DB01282 CarbetocinDrugbanksmall molecule
DB09059 AtosibanDrugbanksmall molecule
DB13929 RelcovaptanDrugbanksmall molecule