Entity Details

Primary name CNR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP34972
EntryNameCNR2_HUMAN
FullNameCannabinoid receptor 2
TaxID9606
Evidenceevidence at protein level
Length360
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesCNR2

GO terms

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GOName
GO:0001975 response to amphetamine
GO:0004930 G protein-coupled receptor activity
GO:0004949 cannabinoid receptor activity
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0019222 regulation of metabolic process
GO:0019233 sensory perception of pain
GO:0030425 dendrite
GO:0030595 leukocyte chemotaxis
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0032229 negative regulation of synaptic transmission, GABAergic
GO:0032496 response to lipopolysaccharide
GO:0033004 negative regulation of mast cell activation
GO:0038171 cannabinoid signaling pathway
GO:0043204 perikaryon
GO:0045759 negative regulation of action potential
GO:0050728 negative regulation of inflammatory response
GO:0051001 negative regulation of nitric-oxide synthase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Perikaryon

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001551 Cannabinoid receptor type 2FamilyFamily
IPR002230 Cannabinoid receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00470 DronabinolDrugbanksmall molecule
DB00486 NabiloneDrugbanksmall molecule
DB02955 Ricinoleic AcidDrugbanksmall molecule
DB06202 LasofoxifeneDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB11755 TetrahydrocannabivarinDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule

Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
CNR2_HUMANTM203_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANYIPF1_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANCOMT_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANADIPO_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANRFT1_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANYIPF4_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANMUC15_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANTM86A_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANSELK_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANYIPF6_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANCCL4_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANS35E4_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANTMPPE_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANTMM60_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANADA21_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANS39A2_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANNRM_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANTM242_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANTMM19_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANFXYD3_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANTSPO2_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANPLCD_HUMANBioGRID, IntAct32296183 details
CNR2_HUMANGPR18_HUMANUniProt29870711 details
CNR2_HUMANCNR1_HUMANUniProt28843453 29870711 details
CNR2_HUMANPDES1_HUMANBioGRID32296183 details
CNR2_HUMANUB2V1_HUMANBioGRID32296183 details
CNR2_HUMANPSMD2_HUMANIntAct25036637 details
CNR2_HUMANSQSTM_HUMANMINT31616248 details
CNR2_HUMANGNA15_HUMANHPRD12095632 details