Entity Details

Primary name LONM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36776
EntryNameLONM_HUMAN
FullNameLon protease homolog, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length959
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesLONP1

GO terms

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GOName
GO:0000002 mitochondrial genome maintenance
GO:0001018 mitochondrial promoter sequence-specific DNA binding
GO:0001666 response to hypoxia
GO:0003697 single-stranded DNA binding
GO:0003727 single-stranded RNA binding
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0007005 mitochondrion organization
GO:0007568 aging
GO:0009725 response to hormone
GO:0010044 response to aluminum ion
GO:0016020 membrane
GO:0016887 ATP hydrolysis activity
GO:0032042 mitochondrial DNA metabolic process
GO:0034599 cellular response to oxidative stress
GO:0042645 mitochondrial nucleoid
GO:0042802 identical protein binding
GO:0043531 ADP binding
GO:0043565 sequence-specific DNA binding
GO:0051131 chaperone-mediated protein complex assembly
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0051880 G-quadruplex DNA binding
GO:0070182 DNA polymerase binding
GO:0070407 oxidation-dependent protein catabolic process

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR003111 Lon, substrate-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR004815 Lon protease, bacterial/eukaryotic-typeFamilyFamily
IPR008268 Peptidase S16, active siteSiteActive site
IPR008269 Peptidase S16, Lon proteolytic domainDomainDomain
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroupFamilyHomologous superfamily
IPR015947 PUA-like superfamilyFamilyHomologous superfamily
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR027065 Lon proteaseFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR027503 Lon protease homologue, chloroplastic/mitochondrialFamilyFamily

Diseases

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