Entity Details

Primary name VKGC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP38435
EntryNameVKGC_HUMAN
FullNameVitamin K-dependent gamma-carboxylase
TaxID9606
Evidenceevidence at protein level
Length758
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesGGCX

GO terms

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GOName
GO:0005789 endoplasmic reticulum membrane
GO:0006464 cellular protein modification process
GO:0007596 blood coagulation
GO:0008488 gamma-glutamyl carboxylase activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0017187 peptidyl-glutamic acid carboxylation
GO:0019842 vitamin binding

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR007782 Vitamin K-dependent gamma-carboxylaseFamilyFamily
IPR011020 HTTMDomainDomain
IPR011051 RmlC-like cupin domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00036 Coagulation factor VIIa Recombinant HumanDrugbankbiotech
DB00100 Coagulation Factor IX (Recombinant)Drugbankbiotech
DB00142 Glutamic acidDrugbanksmall molecule
DB00170 MenadioneDrugbanksmall molecule
DB01022 PhylloquinoneDrugbanksmall molecule
DB01125 AnisindioneDrugbanksmall molecule
DB09332 KappadioneDrugbanksmall molecule
DB13152 Coagulation Factor IX HumanDrugbankbiotech