Entity Details

Primary name SC6A8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48029
EntryNameSC6A8_HUMAN
FullNameSodium- and chloride-dependent creatine transporter 1
TaxID9606
Evidenceevidence at protein level
Length635
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesSLC6A8

GO terms

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GOName
GO:0005308 creatine transmembrane transporter activity
GO:0005309 creatine:sodium symporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006600 creatine metabolic process
GO:0006836 neurotransmitter transport
GO:0006936 muscle contraction
GO:0015881 creatine transmembrane transport
GO:0016021 integral component of membrane
GO:0035725 sodium ion transmembrane transport
GO:0071705 nitrogen compound transport

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000175 Sodium:neurotransmitter symporterFamilyFamily
IPR002984 Sodium:neurotransmitter symporter, creatineFamilyFamily
IPR037272 Sodium:neurotransmitter symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00148 CreatineDrugbanksmall molecule
DB13191 PhosphocreatineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SC6A8_HUMANBKRB1_HUMANBioGRID, MINT28298427 details
SC6A8_HUMANACM5_HUMANBioGRID, MINT28298427 details
SC6A8_HUMANCD59_HUMANHPRD12219031 details