Entity Details

Primary name CX3C1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49238
EntryNameCX3C1_HUMAN
FullNameCX3C chemokine receptor 1
TaxID9606
Evidenceevidence at protein level
Length355
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCX3CR1

GO terms

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GOName
GO:0002052 positive regulation of neuroblast proliferation
GO:0002931 response to ischemia
GO:0004930 G protein-coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0007155 cell adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007267 cell-cell signaling
GO:0007613 memory
GO:0008528 G protein-coupled peptide receptor activity
GO:0009611 response to wounding
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016032 viral process
GO:0016493 C-C chemokine receptor activity
GO:0016495 C-X3-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0019960 C-X3-C chemokine binding
GO:0021626 central nervous system maturation
GO:0030336 negative regulation of cell migration
GO:0032680 regulation of tumor necrosis factor production
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032809 neuronal cell body membrane
GO:0035176 social behavior
GO:0035425 autocrine signaling
GO:0043005 neuron projection
GO:0045087 innate immune response
GO:0045428 regulation of nitric oxide biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0048167 regulation of synaptic plasticity
GO:0048471 perinuclear region of cytoplasm
GO:0050767 regulation of neurogenesis
GO:0050769 positive regulation of neurogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0050901 leukocyte tethering or rolling
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0060074 synapse maturation
GO:0060326 cell chemotaxis
GO:0071222 cellular response to lipopolysaccharide
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0097447 dendritic tree
GO:0098883 synapse pruning
GO:0110091 negative regulation of hippocampal neuron apoptotic process
GO:0150090 multiple spine synapse organization, single dendrite
GO:1900272 negative regulation of long-term synaptic potentiation
GO:1903721 positive regulation of I-kappaB phosphorylation
GO:1904139 regulation of microglial cell migration
GO:1904141 positive regulation of microglial cell migration
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR005387 CX3C chemokine receptor 1FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CX3C1_HUMANCC167_HUMANBioGRID, IntAct32296183 details
CX3C1_HUMANX3CL1_HUMANBioGRID, HPRD, IntAct23125415 9390561 9931005 details
CX3C1_HUMANHIF1A_HUMANBioGRID22952674 details