Entity Details

Primary name TCPG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49368
EntryNameTCPG_HUMAN
FullNameT-complex protein 1 subunit gamma
TaxID9606
Evidenceevidence at protein level
Length545
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCCT3

GO terms

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GOName
GO:0002199 zona pellucida receptor complex
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0006457 protein folding
GO:0007339 binding of sperm to zona pellucida
GO:0016887 ATP hydrolysis activity
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0044183 protein folding chaperone
GO:0044297 cell body
GO:0046931 pore complex assembly
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0070062 extracellular exosome
GO:1901998 toxin transport
GO:1904851 positive regulation of establishment of protein localization to telomere
GO:1904871 positive regulation of protein localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002194 Chaperonin TCP-1, conserved siteSiteConserved site
IPR002423 Chaperonin Cpn60/TCP-1 familyFamilyFamily
IPR012719 T-complex protein 1, gamma subunitFamilyFamily
IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)FamilyFamily
IPR027409 GroEL-like apical domain superfamilyFamilyHomologous superfamily
IPR027410 TCP-1-like chaperonin intermediate domain superfamilyFamilyHomologous superfamily
IPR027413 GroEL-like equatorial domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04395 Phosphoaminophosphonic Acid-Adenylate EsterDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
TCPG_HUMANXRCC6_HUMANBioGRID, HPRD, IntAct15383276 details
TCPG_HUMANRAF1_HUMANBioGRID, HPRD, IntAct12620389 31980649 details
TCPG_HUMANEI2BB_HUMANBioGRID, HPRD, IntAct16169070 details
TCPG_HUMANPA1B2_HUMANBioGRID, HPRD, IntAct16169070 details
TCPG_HUMANZNRD2_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
TCPG_HUMANROA0_HUMANHPRD, IntAct16169070 details
TCPG_HUMANVAV2_HUMANBioGRID, IntAct18654987 details
TCPG_HUMANMK06_HUMANBioGRID, IntAct20936779 26972000 details
TCPG_HUMANOGT1_HUMANBioGRID, IntAct27705803 32994395 details
TCPG_HUMANLNX2_HUMANBioGRID, IntAct27107012 details
TCPG_HUMANUBE2Z_HUMANBioGRID, IntAct32296183 details
TCPG_HUMANSH3B4_HUMANBioGRID, IntAct18654987 details
TCPG_HUMANDEPD5_HUMANBioGRID, IntAct32296183 details
TCPG_HUMANMIPO1_HUMANBioGRID, IntAct25416956 32296183 details
TCPG_HUMANGEMI4_HUMANBioGRID, IntAct32296183 details
TCPG_HUMANPHLP_HUMANBioGRID, IntAct28514442 32296183 details
TCPG_HUMANBUD31_HUMANBioGRID, MINT28298427 details
TCPG_HUMANFANCA_HUMANBioGRID14499622 details
TCPG_HUMANERBB2_HUMANBioGRID, IntAct31980649 details
TCPG_HUMANSTAT3_HUMANDIP24756126 details
TCPG_HUMANRPAC1_HUMANBioGRID, IntAct32296183 details
TCPG_HUMANPTEN_HUMANBioGRID31685992 details
TCPG_HUMANSUMO2_HUMANBioGRID32786267 details
TCPG_HUMAN1433Z_HUMANMINT15161933 details
TCPG_HUMANM3K1_HUMANIntAct14743216 details
TCPG_HUMANTBK1_HUMANIntAct14743216 details
TCPG_HUMANDCAF7_HUMANBioGRID, IntAct25342745 27705803 28514442 details
TCPG_HUMANPHOCN_HUMANBioGRID, IntAct18782753 19156129 details
TCPG_HUMANM3K3_HUMANIntAct14743216 details
TCPG_HUMANCDC20_HUMANBioGRID, IntAct23443559 25306918 26811472 28514442 details
TCPG_HUMANVHL_HUMANBioGRID, HPRD10635329 11865071 21942715 details
TCPG_HUMANCOP1_HUMANBioGRID, IntAct16497536 28514442 details
TCPG_HUMAN2ABA_HUMANBioGRID19156129 details
TCPG_HUMANPSA2_HUMANBioGRID19193609 details
TCPG_HUMANPACRG_HUMANBioGRID14532270 details
TCPG_HUMANWDR82_HUMANBioGRID20516061 details
TCPG_HUMANMET18_HUMANBioGRID23349634 details
TCPG_HUMANLEG3_HUMANBioGRID24755837 details
TCPG_HUMANETKMT_HUMANBioGRID23349634 details
TCPG_HUMANMET23_HUMANBioGRID23349634 details
TCPG_HUMANTTC27_HUMANBioGRID26472760 details
TCPG_HUMANSHAN3_HUMANMINT21653829 details
TCPG_HUMANYAP1_HUMANBioGRID31501420 details
TCPG_HUMANFGF11_HUMANBioGRID28027390 details
TCPG_HUMANHDAC5_HUMANBioGRID21081666 details
TCPG_HUMANSOX2_HUMANBioGRID21280222 details
TCPG_HUMANISG15_HUMANBioGRID16009940 33024031 details
TCPG_HUMANSMAP2_HUMANBioGRID29395067 details
TCPG_HUMANPEX14_HUMANBioGRID21525035 details
TCPG_HUMANCMKMT_HUMANBioGRID23349634 details
TCPG_HUMANF86B2_HUMANBioGRID23349634 details
TCPG_HUMANEFMT3_HUMANBioGRID23349634 details
TCPG_HUMANMT21C_HUMANBioGRID23349634 details
TCPG_HUMANGAN_HUMANBioGRID26460568 details
TCPG_HUMANHSP7C_HUMANHPRD10635329 details