Entity Details

Primary name HINT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49773
EntryNameHINT1_HUMAN
FullNameHistidine triad nucleotide-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length126
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHINT1

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000166 nucleotide binding
GO:0005080 protein kinase C binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0009154 purine ribonucleotide catabolic process
GO:0016787 hydrolase activity
GO:0043530 adenosine 5'-monophosphoramidase activity
GO:0070062 extracellular exosome
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001310 Histidine triad (HIT) proteinFamilyFamily
IPR011146 HIT-like domainDomainDomain
IPR019808 Histidine triad, conserved siteSiteConserved site
IPR036265 HIT-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00131 Adenosine phosphateDrugbanksmall molecule
DB01972 Guanosine-5'-MonophosphateDrugbanksmall molecule
DB02162 5'-O-(N-Ethyl-Sulfamoyl)AdenosineDrugbanksmall molecule
DB02183 Adenosine-5'-ditungstateDrugbanksmall molecule
DB03349 8-Bromo-Adenosine-5'-MonophosphateDrugbanksmall molecule
DB08934 SofosbuvirDrugbanksmall molecule