Entity Details

Primary name BPL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50747
EntryNameBPL1_HUMAN
FullNameBiotin--protein ligase
TaxID9606
Evidenceevidence at protein level
Length726
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHLCS

GO terms

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GOName
GO:0000785 chromatin
GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity
GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity
GO:0005524 ATP binding
GO:0005652 nuclear lamina
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006768 biotin metabolic process
GO:0009305 protein biotinylation
GO:0009374 biotin binding
GO:0016363 nuclear matrix
GO:0016570 histone modification
GO:0018271 biotin-protein ligase activity
GO:0019899 enzyme binding
GO:0070781 response to biotin
GO:0071110 histone biotinylation

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion

Domains

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DomainNameCategoryType
IPR003142 Biotin protein ligase, C-terminalDomainDomain
IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domainDomainDomain
IPR004408 Biotin--acetyl-CoA-carboxylase ligaseFamilyFamily
IPR019197 Biotin-protein ligase, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00121 BiotinDrugbanksmall molecule