Entity Details

Primary name TPIS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP60174
EntryNameTPIS_HUMAN
FullNameTriosephosphate isomerase
TaxID9606
Evidenceevidence at protein level
Length249
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesTPI1

GO terms

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GOName
GO:0004807 triose-phosphate isomerase activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0007275 multicellular organism development
GO:0008929 methylglyoxal synthase activity
GO:0019242 methylglyoxal biosynthetic process
GO:0019563 glycerol catabolic process
GO:0031625 ubiquitin protein ligase binding
GO:0042803 protein homodimerization activity
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
GO:0061621 canonical glycolysis
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000652 Triosephosphate isomeraseFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR020861 Triosephosphate isomerase, active siteSiteActive site
IPR022896 Triosephosphate isomerase, bacterial/eukaryoticFamilyFamily
IPR035990 Triosephosphate isomerase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB01695 N-Hydroxy-4-Phosphono-ButanamideDrugbanksmall molecule
DB02726 2-Phosphoglycolic AcidDrugbanksmall molecule
DB03026 Phosphoglycolohydroxamic AcidDrugbanksmall molecule
DB03132 3-(2-Benzothiazolylthio)-1-Propanesulfonic AcidDrugbanksmall molecule
DB03135 [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic AcidDrugbanksmall molecule
DB03314 5-fluorotryptophanDrugbanksmall molecule
DB03379 2-Carboxyethylphosphonic AcidDrugbanksmall molecule
DB03900 tert-butanolDrugbanksmall molecule
DB04326 Dihydroxyacetone phosphateDrugbanksmall molecule
DB04447 1,4-DithiothreitolDrugbanksmall molecule
DB04510 3-phospho-D-glyceric acidDrugbanksmall molecule
DB07387 3-(BUTYLSULPHONYL)-PROPANOIC ACIDDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule