Entity Details

Primary name PLOD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02809
EntryNamePLOD1_HUMAN
FullNameProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1
TaxID9606
Evidenceevidence at protein level
Length727
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesPLOD1

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0005506 iron ion binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008475 procollagen-lysine 5-dioxygenase activity
GO:0008544 epidermis development
GO:0017185 peptidyl-lysine hydroxylation
GO:0030199 collagen fibril organization
GO:0030867 rough endoplasmic reticulum membrane
GO:0031418 L-ascorbic acid binding
GO:0070062 extracellular exosome
GO:1902494 catalytic complex

Subcellular Location

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Subcellular Location
Rough endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001006 Procollagen-lysine 5-dioxygenase, conserved siteSiteConserved site
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR006620 Prolyl 4-hydroxylase, alpha subunitDomainDomain
IPR029044 Nucleotide-diphospho-sugar transferasesFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00126 Ascorbic acidDrugbanksmall molecule